BAF-312 fumarate
Modify Date: 2024-01-09 17:49:49
BAF-312 fumarate structure
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Common Name | BAF-312 fumarate | ||
|---|---|---|---|---|
| CAS Number | 1234627-85-0 | Molecular Weight | 1149.262 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C62H74F6N4O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAF-312 fumarateSiponimod (BAF-312) hemifumarate is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. Siponimod hemifumarate is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10000, >1000, and 750 nM, respectively). Siponimod hemifumarate can be used for multiple sclerosis (MS) research[1][2]. |
| Name | Siponimod |
|---|---|
| Synonym | More Synonyms |
| Description | Siponimod (BAF-312) hemifumarate is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. Siponimod hemifumarate is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10000, >1000, and 750 nM, respectively). Siponimod hemifumarate can be used for multiple sclerosis (MS) research[1][2]. |
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| Related Catalog | |
| Target |
S1PR1:0.39 nM (EC50) S1PR5:0.98 nM (EC50) S1PR4:750 nM (EC50) S1PR3:>1000 nM (EC50) S1PR2:>10000 nM (EC50) |
| References |
| Molecular Formula | C62H74F6N4O10 |
|---|---|
| Molecular Weight | 1149.262 |
| Exact Mass | 1148.530884 |
| 3-Azetidinecarboxylic acid, 1-[[4-[(1E)-1-[[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]imino]ethyl]-2-ethylphenyl]methyl]-, (2E)-2-butenedioate (2:1) |
| 1-{4-[(1E)-N-{[4-Cyclohexyl-3-(trifluoromethyl)benzyl]oxy}ethanimidoyl]-2-ethylbenzyl}-3-azetidinecarboxylic acid (2E)-2-butenedioate (2:1) |
| MFCD31536984 |
| Siponimod Fumarate |