hDDAH-1-IN-1 TFA

Modify Date: 2024-01-09 18:45:54

hDDAH-1-IN-1 TFA Structure
hDDAH-1-IN-1 TFA structure
Common Name hDDAH-1-IN-1 TFA
CAS Number 1229238-70-3 Molecular Weight 416.32
Density N/A Boiling Point N/A
Molecular Formula C12H22F6N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hDDAH-1-IN-1 TFA


hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].

 Names

Name hDDAH-1-IN-1 TFA

 hDDAH-1-IN-1 TFA Biological Activity

Description hDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].
Related Catalog
In Vitro hDDAH-1-IN-1 TFA potently inhibits hDDAH-1 (Ki = 18 µM) without significantly affecting NOSs and arginase[1].
References

[1]. Lunk I, et al. Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J Med Chem. 2019 Dec 31.

 Chemical & Physical Properties

Molecular Formula C12H22F6N4O5
Molecular Weight 416.32