PF-04634817

Modify Date: 2024-04-05 18:52:05

PF-04634817 structure	Common Name	PF-04634817
	CAS Number	1228111-63-4	Molecular Weight	511.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₆F₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF-04634817

PF-0463481, an oral CCR2/5 dual antagonist, with a favorable ocular safety profile versus intravitreal therapies[1]. PF-0463481 is safe and well-tolerated and being developed for the treatment of diabetic nephropathy[2].

Name	PF-04634817

Description	PF-0463481, an oral CCR2/5 dual antagonist, with a favorable ocular safety profile versus intravitreal therapies[1]. PF-0463481 is safe and well-tolerated and being developed for the treatment of diabetic nephropathy[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Inflammation/Immunology
Target	CCR2 CCR5
References	[1]. Gale JD, et al. A CCR2/5 Inhibitor, PF-04634817, Is Inferior to Monthly Ranibizumab in the Treatment of Diabetic Macular Edema. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2659-2669. [2]. Gale JD, et al. Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy. Kidney Int Rep. 2018 Aug 3;3(6):1316-1327.

Molecular Formula	C₂₅H₃₆F₃N₅O₃
Molecular Weight	511.58

DC Chemicals Limited
China
Product Name: PF-04634817
Price: $Inquiry/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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