BI-4464

Modify Date: 2024-01-10 13:02:25

BI-4464 Structure
BI-4464 structure
Common Name BI-4464
CAS Number 1227948-02-8 Molecular Weight 555.55
Density N/A Boiling Point N/A
Molecular Formula C28H28F3N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-4464


BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1].

 Names

Name BI-4464

 BI-4464 Biological Activity

Description BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1].
Related Catalog
Target

IC50: 17 nM (PTK2/FAK)[1].

References

[1]. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.

 Chemical & Physical Properties

Molecular Formula C28H28F3N5O4
Molecular Weight 555.55
Storage condition 2-8℃
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: BI-4464
  • Price: $750.0/100mg $1400.0/250mg $2700.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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