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  • DC Chemicals Limited
  • China
  • Product Name: BI-4464
  • Price: $750.0/100mg $1400.0/250mg $2700.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1227948-02-8

1227948-02-8 structure
1227948-02-8 structure
  • Name: BI-4464
  • Chemical Name: BI-4464
  • CAS Number: 1227948-02-8
  • Molecular Formula: C28H28F3N5O4
  • Molecular Weight: 555.55
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
  • Create Date: 2019-06-01 19:24:46
  • Modify Date: 2024-01-10 13:02:25
  • BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1].

Name BI-4464
Description BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1].
Related Catalog
Target

IC50: 17 nM (PTK2/FAK)[1].

References

[1]. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.

Molecular Formula C28H28F3N5O4
Molecular Weight 555.55
Storage condition 2-8℃