CMB-087229

Modify Date: 2025-09-01 18:57:35

CMB-087229 structure	Common Name	CMB-087229
	CAS Number	1227692-67-2	Molecular Weight	259.09
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₈Cl₂N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CMB-087229

CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].

Name	5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
Synonym	More Synonyms

Description	CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527.

Molecular Formula	C₁₀H₈Cl₂N₂O₂
Molecular Weight	259.09

MFCD31745789

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CMB-087229
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Purity: 98.0%
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