CMB-087229

Names

[ Name ]:
CMB-087229

[Synonym ]:
MFCD31745789

Biological Activity

[Description]:

CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₈Cl₂N₂O₂

[ Molecular Weight ]:
259.09

Related Compounds

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