1227692-67-2

1227692-67-2 structure

1227692-67-2 structure

Name: CMB-087229
Chemical Name: 5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
CAS Number: 1227692-67-2
Molecular Formula: C₁₀H₈Cl₂N₂O₂
Molecular Weight: 259.09
Create Date: 2022-11-22 13:03:46
Modify Date: 2024-04-05 23:03:06
CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].

Name	5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
Synonyms	MFCD31745789

Description	CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527.

Molecular Formula	C₁₀H₈Cl₂N₂O₂
Molecular Weight	259.09