GNX-865

Modify Date: 2025-08-28 11:03:37

GNX-865 Structure
GNX-865 structure
Common Name GNX-865
CAS Number 1223568-82-8 Molecular Weight 303.742
Density N/A Boiling Point N/A
Molecular Formula C16H14ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GNX-865


GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction.

 Names

Name GNX-865

 GNX-865 Biological Activity

Description GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction.
References References 1. Fancelli D, et al. J Med Chem. 2014 Jun 26;57(12):5333-47. 2. Roy S, et al. ChemMedChem. 2015 Oct;10(10):1655-71. View Related Products by Target Mitochondrial Permeability Transition Pore (mPTP)

 Chemical & Physical Properties

Molecular Formula C16H14ClNO3
Molecular Weight 303.742
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