GNX-865

Names

[ Name ]:
GNX-865

Biological Activity

[Description]:

GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction.

[References]

References 1. Fancelli D, et al. J Med Chem. 2014 Jun 26;57(12):5333-47. 2. Roy S, et al. ChemMedChem. 2015 Oct;10(10):1655-71. View Related Products by Target Mitochondrial Permeability Transition Pore (mPTP)

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₄ClNO₃

[ Molecular Weight ]:
303.742

Related Compounds

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