1223568-82-8
1223568-82-8 structure
- Name: GNX-865
- Chemical Name: GNX-865
- CAS Number: 1223568-82-8
- Molecular Formula: C16H14ClNO3
- Molecular Weight: 303.742
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-01-11 21:32:50
- Modify Date: 2024-04-06 07:36:53
-
GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction.
| Name | GNX-865 |
|---|
| Description | GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction. |
|---|---|
| References | References 1. Fancelli D, et al. J Med Chem. 2014 Jun 26;57(12):5333-47. 2. Roy S, et al. ChemMedChem. 2015 Oct;10(10):1655-71. View Related Products by Target Mitochondrial Permeability Transition Pore (mPTP) |
| Molecular Formula | C16H14ClNO3 |
|---|---|
| Molecular Weight | 303.742 |