Cetirizine-d4

Modify Date: 2025-08-25 15:40:44

Cetirizine-d4 structure	Common Name	Cetirizine-d4
	CAS Number	1219803-84-5	Molecular Weight	392.91200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₁D₄ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cetirizine-d4

Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

Name	Cetirizine-D4
Synonym	More Synonyms

Description	Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H1 receptor
References	[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993. [2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

Molecular Formula	C₂₁H₂₁D₄ClN₂O₃
Molecular Weight	392.91200
Exact Mass	392.18000
PSA	53.01000
LogP	3.02400
InChIKey	ZKLPARSLTMPFCP-QZPARXMSSA-N
SMILES	O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1

(±)-Cetirizine-d4 (ethoxy-d4)

(±)-Cetirizine-d4

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Cetirizine-d4

Use of Cetirizine-d4

Names

Cetirizine-d4 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.