Cetirizine-d4

Modify Date: 2024-01-03 11:58:21

Cetirizine-d4 structure	Common Name	Cetirizine-d4
	CAS Number	1219803-84-5	Molecular Weight	392.91200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₁D₄ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cetirizine-d4

Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

Name	Cetirizine-D4
Synonym	More Synonyms

Description	Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H1 receptor
References	[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993. [2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.

Molecular Formula	C₂₁H₂₁D₄ClN₂O₃
Molecular Weight	392.91200
Exact Mass	392.18000
PSA	53.01000
LogP	3.02400

(±)-Cetirizine-d4 (ethoxy-d4)

(±)-Cetirizine-d4

Cetirizine-d4

Use of Cetirizine-d4

Names

Cetirizine-d4 Biological Activity

Chemical & Physical Properties

Synonyms