Cetirizine D8
Modify Date: 2025-08-25 12:55:18
Cetirizine D8 structure
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Common Name | Cetirizine D8 | ||
|---|---|---|---|---|
| CAS Number | 774596-22-4 | Molecular Weight | 469.85900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H17D8ClN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cetirizine D8Cetirizine D8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3]. |
| Name | Cetirizine-D8 |
|---|---|
| Synonym | More Synonyms |
| Description | Cetirizine D8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
H1 receptor |
| References |
[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993. |
| Molecular Formula | C21H17D8ClN2O3 |
|---|---|
| Molecular Weight | 469.85900 |
| Exact Mass | 468.15900 |
| PSA | 53.01000 |
| LogP | 4.62800 |
| InChIKey | ZKLPARSLTMPFCP-BGKXKQMNSA-N |
| SMILES | O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 |
| [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethoxy]acetic acid |
| Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl-2,2,3,3,5,5,6,6-d8]ethoxy]- |