N-Nitroso-diethylamine D10

Modify Date: 2024-01-21 11:51:14

N-Nitroso-diethylamine D10 Structure
N-Nitroso-diethylamine D10 structure
Common Name N-Nitroso-diethylamine D10
CAS Number 1219794-54-3 Molecular Weight 112.19661778
Density N/A Boiling Point N/A
Molecular Formula (C2D5)2NNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Nitroso-diethylamine D10


N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

 Names

Name N-Nitrosodiethylamine-d10
Synonym More Synonyms

 N-Nitroso-diethylamine D10 Biological Activity

Description N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula (C2D5)2NNO
Molecular Weight 112.19661778

 Safety Information

Hazard Codes Xn

 Synonyms

MFCD06658574