acetaminophen glucuronide sodium salt

Modify Date: 2024-01-05 21:55:01

acetaminophen glucuronide sodium salt Structure
acetaminophen glucuronide sodium salt structure
Common Name acetaminophen glucuronide sodium salt
CAS Number 120595-80-4 Molecular Weight 349.27
Density N/A Boiling Point N/A
Molecular Formula C14H16NNaO8 Melting Point 232-233ºC (dec)
MSDS Chinese USA Flash Point N/A

 Use of acetaminophen glucuronide sodium salt


Acetaminophen glucuronide is a safe and effectiveantipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liverand kidney [1].

 Names

Name p-Acetamidophenyl β-D-glucuronide sodium salt
Synonym More Synonyms

 acetaminophen glucuronide sodium salt Biological Activity

Description Acetaminophen glucuronide is a safe and effectiveantipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liverand kidney [1].
Related Catalog
References

[1]. MazaleuskayaLL, et al. PharmGKB summary: pathways of acetaminophen metabolism at thetherapeutic versus toxic doses. Pharmacogenet Genomics. 2015 Aug;25(8):416-26.  

 Chemical & Physical Properties

Melting Point 232-233ºC (dec)
Molecular Formula C14H16NNaO8
Molecular Weight 349.27
Exact Mass 349.07700
PSA 148.38000
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~84%

acetaminophen glucuronide sodium salt Structure

acetaminophen g...

CAS#:120595-80-4

Literature: Hayes, John A.; Eccles, Kevin S.; Lawrence, Simon E.; Moynihan, Humphrey A. Carbohydrate Research, 2012 , vol. 349, p. 108 - 112

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acetaminophen glucuronide sodium salt Structure

acetaminophen g...

CAS#:120595-80-4

Literature: Carbohydrate Research, , vol. 349, p. 108 - 112

~%

acetaminophen glucuronide sodium salt Structure

acetaminophen g...

CAS#:120595-80-4

Literature: Carbohydrate Research, , vol. 349, p. 108 - 112

 Articles8

More Articles
Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.

Drug Metab. Dispos. 43(1) , 147-53, (2014)

This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

Development of a SPE-UHPLC-MS/MS methodology for the determination of non-steroidal anti-inflammatory and analgesic pharmaceuticals in seawater.

J. Pharm. Biomed. Anal. 106 , 61-70, (2015)

An analytical methodology for the simultaneous determination of seven pharmaceuticals and two metabolites belonging to the non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics therapeutic gro...

The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide.

Eur. J. Drug Metab. Pharmacokinet. 40 , 163-70, (2015)

The study aimed to examine the effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite, paracetamol glucuronide. Both drugs share metabolic pathways in the liver...

 Synonyms

MFCD00153898
ACETAMINOPHEN GLUCURONIDE SODIUM SALT
Acetaminophen glucuronide,Paracetamol glucuronide
Acetaminophen glucuronide Paracetamol glucuronide