Indole-3-acetamide-d5

Modify Date: 2024-01-22 18:32:31

Indole-3-acetamide-d5 Structure
Indole-3-acetamide-d5 structure
Common Name Indole-3-acetamide-d5
CAS Number 1204700-53-7 Molecular Weight 174.199
Density 1.3±0.1 g/cm3 Boiling Point 407.1±47.0 °C at 760 mmHg
Molecular Formula C10H10N2O Melting Point N/A
MSDS N/A Flash Point 200.0±29.3 °C

 Use of Indole-3-acetamide-d5


Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].

 Names

Name 3-Indoleacetamide
Synonym More Synonyms

 Indole-3-acetamide-d5 Biological Activity

Description Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Thomas Lehmann, et al. Indole-3-acetamide-dependent auxin biosynthesis: a widely distributed way of indole-3-acetic acid production? Eur J Cell Biol. 2010 Dec;89(12):895-905.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 407.1±47.0 °C at 760 mmHg
Molecular Formula C10H10N2O
Molecular Weight 174.199
Flash Point 200.0±29.3 °C
Exact Mass 174.079315
LogP 0.79
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.650

 Synonyms

Indole-3-acetamide
1H-Indole-3-ethanimidic acid
2-(1H-Indol-3-yl)acetamide
1H-Indole-3-acetamide
3-Indoleacetamide