1204700-53-7

1204700-53-7 structure
1204700-53-7 structure
  • Name: Indole-3-acetamide-d5
  • Chemical Name: 3-Indoleacetamide
  • CAS Number: 1204700-53-7
  • Molecular Formula: C10H10N2O
  • Molecular Weight: 174.199
  • Catalog: Research Areas Others
  • Create Date: 2018-02-18 17:36:03
  • Modify Date: 2024-01-22 18:32:31
  • Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].

Name 3-Indoleacetamide
Synonyms Indole-3-acetamide
1H-Indole-3-ethanimidic acid
2-(1H-Indol-3-yl)acetamide
1H-Indole-3-acetamide
3-Indoleacetamide
Description Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Thomas Lehmann, et al. Indole-3-acetamide-dependent auxin biosynthesis: a widely distributed way of indole-3-acetic acid production? Eur J Cell Biol. 2010 Dec;89(12):895-905.  

Density 1.3±0.1 g/cm3
Boiling Point 407.1±47.0 °C at 760 mmHg
Molecular Formula C10H10N2O
Molecular Weight 174.199
Flash Point 200.0±29.3 °C
Exact Mass 174.079315
LogP 0.79
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.650