AS1949490

Modify Date: 2025-08-25 15:02:02

AS1949490 structure	Common Name	AS1949490
	CAS Number	1203680-76-5	Molecular Weight	371.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈ClNO₂S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of AS1949490

AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2].

Name	3-[(4-Chlorobenzyl)oxy]-N-[(1S)-1-phenylethyl]-2-thiophenecarboxa mide
Synonym	More Synonyms

Description	AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM. AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Metabolic Disease
Target	IC50: 620 nM (SHIP-2)[1].
References	[1]. Suwa A, et al. Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2. Br J Pharmacol. 2009 Oct;158(3):879-87. [2]. Suwa A, et al. Glucose metabolism activation by SHIP2 inhibitors via up-regulation of GLUT1 gene in L6 myotubes. Eur J Pharmacol. 2010 Sep 10;642(1-3):177-82.

Molecular Formula	C₂₀H₁₈ClNO₂S
Molecular Weight	371.88
Exact Mass	371.07500
PSA	70.06000
LogP	6.04630

AS1949490 MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
RIDADR	NONH for all modes of transport

3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]- 2-thiophenecarboxamide AS 1949490

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AS1949490
Price: Check
Purity: 98.0%
Delivery: 10 Day
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: AS-1949490
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
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DC Chemicals Limited
China
Product Name: AS-1949490
Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/250mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]thiophene-2-carboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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AS1949490

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.