(5Z)-2-amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one
Modify Date: 2024-04-09 10:48:08
(5Z)-2-amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one structure
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Common Name | (5Z)-2-amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one | ||
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| CAS Number | 1198098-03-1 | Molecular Weight | 264.300 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 454.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C12H12N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 228.9±31.5 °C | |
Use of (5Z)-2-amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-oneGSK-3β inhibitor 10 (compound 14a) is a highly potent GSK-3β inhibitor with an IC50 value of 80.5 nM. GSK-3β inhibitor 10 can be used for researching Alzheimer’s disease[1]. |
| Name | 5-(3,4-Dimethoxy-benzylidene)-2-imino-thiazolidin-4-one |
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| Synonym | More Synonyms |
| Description | GSK-3β inhibitor 10 (compound 14a) is a highly potent GSK-3β inhibitor with an IC50 value of 80.5 nM. GSK-3β inhibitor 10 can be used for researching Alzheimer’s disease[1]. |
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| Related Catalog | |
| Target |
GSK-3β:80.5 nM (IC50) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 454.8±55.0 °C at 760 mmHg |
| Molecular Formula | C12H12N2O3S |
| Molecular Weight | 264.300 |
| Flash Point | 228.9±31.5 °C |
| Exact Mass | 264.056854 |
| LogP | 1.73 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.630 |
| Storage condition | -20°C |
| 4(5H)-Thiazolone, 2-amino-5-[(3,4-dimethoxyphenyl)methylene]-, (5Z)- |
| 5-(3,4-Dimethoxy-benzylidene)-2-imino-thiazolidin-4-one |
| (5Z)-2-Amino-5-(3,4-dimethoxybenzylidene)-1,3-thiazol-4(5H)-one |