3,4,5,6-Tetrachlorobenzene-1,2-diol

Modify Date: 2025-08-22 14:57:53

3,4,5,6-Tetrachlorobenzene-1,2-diol structure	Common Name	3,4,5,6-Tetrachlorobenzene-1,2-diol
	CAS Number	1198-55-6	Molecular Weight	247.891
	Density	1.8±0.1 g/cm3	Boiling Point	309.1±37.0 °C at 760 mmHg
	Molecular Formula	C₆H₂Cl₄O₂	Melting Point	184-186°C (dec.)
	MSDS	USA	Flash Point	140.7±26.5 °C
	Symbol	GHS05, GHS07, GHS09	Signal Word	Danger

Use of 3,4,5,6-Tetrachlorobenzene-1,2-diol

Tetrachlorocatechol is a metabolite of pentachlorophenol. Tetrachlorocatechol is one of the most toxic chlorinated catechol produced by the chlorobleaching of pulp and frequently found in the kraft pulp mill effluents[1][2].

Name	tetrachlorocatechol
Synonym	More Synonyms

Description	Tetrachlorocatechol is a metabolite of pentachlorophenol. Tetrachlorocatechol is one of the most toxic chlorinated catechol produced by the chlorobleaching of pulp and frequently found in the kraft pulp mill effluents[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. G. Renner, et al. Acute toxicities of pentachlorophenol, pentachloroanisole, tetrachlorohydroquinone, tetrachlorocatechol, tetrachlororesorcinol, tetrachlorodimethoxybenzenes and tetrachlorobenzenediol diacetates administered to mice, Toxicological & Environmental Chemistry, 11:1, 37-50. [2]. Mukherjee, et al. Evaluation of Acute Toxicity Levels and Ethological Responses Under Tetrachlorocatechol Exposure in Common Carp, Cyprinus carpio (Linnaeus). Proc Zool Soc 67, 108–113 (2014).

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. G. Renner, et al. Acute toxicities of pentachlorophenol, pentachloroanisole, tetrachlorohydroquinone, tetrachlorocatechol, tetrachlororesorcinol, tetrachlorodimethoxybenzenes and tetrachlorobenzenediol diacetates administered to mice, Toxicological & Environmental Chemistry, 11:1, 37-50.

[2]. Mukherjee, et al. Evaluation of Acute Toxicity Levels and Ethological Responses Under Tetrachlorocatechol Exposure in Common Carp, Cyprinus carpio (Linnaeus). Proc Zool Soc 67, 108–113 (2014).

Density	1.8±0.1 g/cm3
Boiling Point	309.1±37.0 °C at 760 mmHg
Melting Point	184-186°C (dec.)
Molecular Formula	C₆H₂Cl₄O₂
Molecular Weight	247.891
Flash Point	140.7±26.5 °C
Exact Mass	245.880890
PSA	40.46000
LogP	4.74
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.662
Storage condition	2-8°C

3,4,5,6-Tetrachlorobenzene-1,2-diol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX2449000

CHEMICAL NAME :: Pyrocatechol, tetrachloro-

CAS REGISTRY NUMBER :: 1198-55-6

BEILSTEIN REFERENCE NO. :: 1876366

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H2-Cl4-O2

MOLECULAR WEIGHT :: 247.88

WISWESSER LINE NOTATION :: QR BQ CG DG EG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,526,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,526,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 318 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - muscle weakness

REFERENCE :: TECSDY Toxicological and Environmental Chemistry. (Gordon & Breach Science Pub. Inc., 1 Park Ave., New York, NY 10016) V.3(3/4)- 1981- Volume(issue)/page/year: 11,37,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 136 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 40,63,1978

Symbol	GHS05, GHS07, GHS09
Signal Word	Danger
Hazard Statements	H302-H318-H400
Precautionary Statements	P273-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R20/22
Safety Phrases	S26-S36/37/39-S39
RIDADR	2811
RTECS	UX2449000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2908199090

HS Code	2908199090
Summary	HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Polyhalogenated benzo- and naphthoquinones are potent inhibitors of plant and bacterial ureases.

FEBS Lett. 555(2) , 367-70, (2003)

Polyhalogenated benzo- and naphthoquinones were found to be potent inhibitors of pure ureases from Bacillus pasteurii and Canavalia ensiformis. They also inhibited ureases in whole cells of Helicobact...

Oxidative double dehalogenation of tetrachlorocatechol by a bio-inspired CuII complex: formation of chloranilic acid.

Chemistry 14(18) , 5567-76, (2008)

Copper(II) complexes of the potentially tripodal N,N,O ligand 3,3-bis(1-methylimidazol-2-yl)propionate (L1) and its conjugate acid HL1 have been synthesised and structurally and spectroscopically char...

Synergistic cytotoxic effect of tetrachlorocatechol and sodium azide in Escherichia coli: toxicity, metabolism, and mechanistic aspects.

Environ. Toxicol. Chem. 28(7) , 1380-9, (2009)

Pentachlorophenol (PCP) is used in industrial and domestic applications, including as a biocide and a wood preservative. Metabolism of PCP undergoes oxidative dechlorination, forming tetrachlorocatech...

1,2-Benzenediol, 3,4,5,6-tetrachloro-

MFCD00002190

3,4,5,6-Tetrachloro-1,2-benzenediol (9CI)

3,4,5,6-tetrachlorobenzene-1,2-diol

3,4,5,6-Tetrachloro-1,2-benzenediol

TETRACHLOROCATECHOL