Propargyl-PEG8-NH2

Modify Date: 2025-08-25 11:48:32

Propargyl-PEG8-NH2 Structure
Propargyl-PEG8-NH2 structure
Common Name Propargyl-PEG8-NH2
CAS Number 1196732-52-1 Molecular Weight 407.499
Density 1.1±0.1 g/cm3 Boiling Point 477.4±40.0 °C at 760 mmHg
Molecular Formula C19H37NO8 Melting Point N/A
MSDS N/A Flash Point 232.8±21.0 °C

 Use of Propargyl-PEG8-NH2


Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine
Synonym More Synonyms

 Propargyl-PEG8-NH2 Biological Activity

Description Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Genady AR, et al. Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That TargetProstate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy. J Med Chem. 2016 Mar 24;59(6):2660-73.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 477.4±40.0 °C at 760 mmHg
Molecular Formula C19H37NO8
Molecular Weight 407.499
Flash Point 232.8±21.0 °C
Exact Mass 407.251923
LogP -2.61
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.466

 Safety Information

Hazard Codes Xi

 Synonyms

3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine
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