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1196732-52-1

1196732-52-1 structure
1196732-52-1 structure
  • Name: Propargyl-PEG8-NH2
  • Chemical Name: 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine
  • CAS Number: 1196732-52-1
  • Molecular Formula: C19H37NO8
  • Molecular Weight: 407.499
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-13 02:29:35
  • Modify Date: 2024-01-06 09:27:43
  • Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine
Synonyms 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-amine
Description Propargyl-PEG8-NH2 (compound 3b) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Genady AR, et al. Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That TargetProstate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy. J Med Chem. 2016 Mar 24;59(6):2660-73.

Density 1.1±0.1 g/cm3
Boiling Point 477.4±40.0 °C at 760 mmHg
Molecular Formula C19H37NO8
Molecular Weight 407.499
Flash Point 232.8±21.0 °C
Exact Mass 407.251923
LogP -2.61
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.466
Hazard Codes Xi