2055014-96-3
2055014-96-3 structure
- Name: Propargyl-PEG8-Boc
- Chemical Name: Propargyl-PEG8-t-butyl ester
- CAS Number: 2055014-96-3
- Molecular Formula: C24H44O10
- Molecular Weight: 492.600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-14 13:35:37
- Modify Date: 2024-01-08 18:08:10
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Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
| Name | Propargyl-PEG8-t-butyl ester |
|---|---|
| Synonyms |
2-Methyl-2-propanyl 4,7,10,13,16,19,22,25-octaoxaoctacos-27-yn-1-oate
MFCD28976700 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid, 1,1-dimethylethyl ester |
| Description | Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2. |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 528.4±45.0 °C at 760 mmHg |
| Molecular Formula | C24H44O10 |
| Molecular Weight | 492.600 |
| Flash Point | 220.3±28.8 °C |
| Exact Mass | 492.293457 |
| LogP | -0.54 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.460 |
| Storage condition | 2-8°C |