5-Methyl-2'-C-methyluridine

Modify Date: 2024-01-12 11:11:04

5-Methyl-2'-C-methyluridine Structure
5-Methyl-2'-C-methyluridine structure
Common Name 5-Methyl-2'-C-methyluridine
CAS Number 119410-84-3 Molecular Weight 272.25
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C11H16N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methyl-2'-C-methyluridine


2’-β-C-Methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2'-C-methylthymidine
Synonym More Synonyms

 5-Methyl-2'-C-methyluridine Biological Activity

Description 2’-β-C-Methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C11H16N2O6
Molecular Weight 272.25
Exact Mass 272.100830
PSA 124.78000
LogP -0.26
Index of Refraction 1.597

 Synonyms

1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Uridine, 5-methyl-2'-C-methyl-
2'-C-METHYL-5-METHYLURIDINE
5-Methyl-2'-C-methyluridine
5-METHYL-2'-C-METHYL-URIDINE