Lck Inhibitor III

Modify Date: 2023-01-14 20:27:13

Lck Inhibitor III structure	Common Name	Lck Inhibitor III
	CAS Number	1188890-30-3	Molecular Weight	478.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₈N₆O₃・H₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lck Inhibitor III

Lck Inhibitor III (compound 12h) is a potent Lck inhibitor, with an IC50 of 867 nM. Lck Inhibitor III inhibits IL-2 synthesis in Jurkat cells, with an IC50 of 1.270 μM[1].

Name	Lck Inhibitor III
Synonym	More Synonyms

Description	Lck Inhibitor III (compound 12h) is a potent Lck inhibitor, with an IC50 of 867 nM. Lck Inhibitor III inhibits IL-2 synthesis in Jurkat cells, with an IC50 of 1.270 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src
Target	IL-2 Lck:867 nM (IC50)
References	[1]. Sabat M, et al. The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck). Bioorg Med Chem Lett. 2006 Dec 1;16(23):5973-7.

Molecular Formula	C₂₅H₂₈N₆O₃・H₂O
Molecular Weight	478.55
Water Solubility	Soluble in DMSO (100 mg/ml), and ethanol (25 mg/ml).

2-(1H-Benzo[d]imidazol-1-yl)-N-(5-methoxy-2-methylphenyl)-6-(2-morpholinoethoxy)pyrimidin-4-amine, hydrate

Lck Inhibitor III

Use of Lck Inhibitor III

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Lck Inhibitor III Biological Activity

Chemical & Physical Properties

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