quinoline-3-carboxylic acid

Modify Date: 2024-01-10 15:50:37

quinoline-3-carboxylic acid Structure
quinoline-3-carboxylic acid structure
Common Name quinoline-3-carboxylic acid
CAS Number 118803-81-9 Molecular Weight 442.440
Density N/A Boiling Point 555.8ºC at 760 mmHg
Molecular Formula C22H23FN4O5 Melting Point 277-280ºC(lit.)
MSDS N/A Flash Point 289.9ºC

 Use of quinoline-3-carboxylic acid


Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration[1].

 Names

Name 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid,pyridine-3-carboxylic acid
Synonym More Synonyms

 quinoline-3-carboxylic acid Biological Activity

Description Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration[1].
Related Catalog
In Vivo Norfloxacin nicotinate (5 and/or 25 mg/L) significantly induces antioxidant enzymes activities and the mRNA levels of genes related to antioxidant enzymes and innate immune system in zebrafish larvae[1].
References

[1]. Liang X, et al. Effects of norfloxacin nicotinate on the early life stage of zebrafish (Danio rerio): Developmental toxicity, oxidative stress and immunotoxicity. Fish Shellfish Immunol. 2020 Jan;96:262-269.

 Chemical & Physical Properties

Boiling Point 555.8ºC at 760 mmHg
Melting Point 277-280ºC(lit.)
Molecular Formula C22H23FN4O5
Molecular Weight 442.440
Flash Point 289.9ºC
Exact Mass 442.165253
PSA 124.76000
LogP 2.44190
Vapour Pressure 3.45E-13mmHg at 25°C

 Safety Information

Safety Phrases S22
WGK Germany 3

 Synonyms

3-Pyridinecarboxylic acid, compd. with 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (1:1)
Norfloxacin nicotinate
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid - nicotinic acid (1:1)
1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid - nicotinic acid (1:1)
Top Suppliers:I want be here



Get all suppliers and price by the below link:

quinoline-3-carboxylic acid suppliers

quinoline-3-carboxylic acid price