N-methylacrylamide

Modify Date: 2025-08-25 17:59:57

N-methylacrylamide structure	Common Name	N-methylacrylamide
	CAS Number	1187-59-3	Molecular Weight	85.104
	Density	0.9±0.1 g/cm3	Boiling Point	207.7±13.0 °C at 760 mmHg
	Molecular Formula	C₄H₇NO	Melting Point	N/A
	MSDS	N/A	Flash Point	103.6±4.8 °C

Name	N-methylprop-2-enamide
Synonym	More Synonyms

Density	0.9±0.1 g/cm3
Boiling Point	207.7±13.0 °C at 760 mmHg
Molecular Formula	C₄H₇NO
Molecular Weight	85.104
Flash Point	103.6±4.8 °C
Exact Mass	85.052765
PSA	29.10000
LogP	-0.68
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.415
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AS3676000

CHEMICAL NAME :: Acrylamide, N-methyl-

CAS REGISTRY NUMBER :: 1187-59-3

BEILSTEIN REFERENCE NO. :: 1737696

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C4-H7-N-O

MOLECULAR WEIGHT :: 85.12

WISWESSER LINE NOTATION :: 1U1VM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 476 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 477 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6500 mg/kg/13W-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - structural change in nerve or sheath Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4988 mg/kg/18W-C

TOXIC EFFECTS :: Behavioral - muscle weakness

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2587 mg/kg/8W-I

TOXIC EFFECTS :: Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2544 mg/kg

SEX/DURATION :: male 16 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 595 gm/kg

SEX/DURATION :: male 5 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 595 gm/kg

SEX/DURATION :: male 5 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 596 mg/kg/5W (Continuous)

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,201,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1046 No. of Facilities: 122 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 367 (estimated)

Hazard Codes	Xi
Risk Phrases	R20/21/22
Safety Phrases	S23;S26;S36/S37/S39
RIDADR	UN 2810
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2924199090

DIEA

CAS#:7087-68-5

Acrylyl chloride

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N-methylacrylamide

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Literature: US5607960 A1, ;

1-(methylcarbam...

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N-methylacrylamide

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Literature: Journal of the American Chemical Society, , vol. 71, p. 648,650

Acrylyl chloride

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methylamine

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N-methylacrylamide

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3-Hydroxy-N-met...

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N-methylacrylamide

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β-Propiolactone

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methylamine

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N-methylacrylamide

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N-methyl-N-prop...

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N-methylacrylamide

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Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 318, p. 471 - 478

methylamine

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Ethyl acrylate ...

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N-methylacrylamide

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methylamine

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Acetylene

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N-methylacrylamide

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1-(methylcarbam...

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N-methylacrylamide

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ch3cho

CAS#:75-07-0

acetic acid

CAS#:64-19-7

Literature: Journal of the American Chemical Society, , vol. 71, p. 648,650

Precursor 9
CAS#:7087-68-5 DIEA CAS#:814-68-6 Acrylyl chloride CAS#:5450-85-1 1-(methylcarbam... CAS#:74-89-5 methylamine
CAS#:6830-81-5 3-Hydroxy-N-met... CAS#:57-57-8 β-Propiolactone CAS#:24685-31-2 N-methyl-N-prop... CAS#:140-88-5 Ethyl acrylate ...
CAS#:74-86-2 Acetylene
DownStream 3
CAS#:1001346-35-5 3-(2-methoxyeth... CAS#:2680-03-7 Acryloyldimethy... CAS#:50836-82-3 N-methyl-3-(met...

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-Methyl-2-propenamide

2-Propenamide,N-methyl

N-methylprop-2-enamide

EINECS 214-700-0

(meth-)acrylamide

2-Propenamide, N-methyl-

N-Methyl-acrylamid

N-Methylacrylamide

Acrylamide,N-methyl

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: N-methylacrylamide
Price: Check
Purity: 98.0%
Delivery: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: N-methylacrylamide
Price: ￥338.0/50mg ￥998.0/250mg
Purity: 98.0%
Delivery: 3 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-methylacrylamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: N-methylacrylamide
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/25g
Purity: 98.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

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N-methylacrylamide

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Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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Synthetic Route

Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.