4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride
Modify Date: 2024-03-02 20:16:38
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride structure
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Common Name | 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride | ||
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| CAS Number | 1185136-22-4 | Molecular Weight | 518.133 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H40ClN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochlorideLP 12 hydrochloride (compound 21) is a potent and selective 5-HT7 receptor agonist with a Ki of 0.13 nM. LP 12 hydrochloride displays selectivity for 5-HT7 over D2, 5-HT1A and 5-HT2A receptors (Ki values are 224 nM, 60.9 nM and >1000 nM, respectively)[1]. |
| Name | 6-[4-(2-Biphenylyl)-1-piperazinyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)hexanamide hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | LP 12 hydrochloride (compound 21) is a potent and selective 5-HT7 receptor agonist with a Ki of 0.13 nM. LP 12 hydrochloride displays selectivity for 5-HT7 over D2, 5-HT1A and 5-HT2A receptors (Ki values are 224 nM, 60.9 nM and >1000 nM, respectively)[1]. |
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| Related Catalog | |
| Target |
5-HT7 Receptor:0.13 nM (IC50) 5-HT1A Receptor:60.9 nM (IC50) 5-HT2A Receptor:1464 nM (IC50) |
| References |
| Molecular Formula | C32H40ClN3O |
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| Molecular Weight | 518.133 |
| Exact Mass | 517.286011 |
| 1-Piperazinehexanamide, 4-[1,1'-biphenyl]-2-yl-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1) |
| 6-[4-(Biphenyl-2-yl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide hydrochloride (1:1) |
| 6-[4-(2-Biphenylyl)-1-piperazinyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)hexanamide hydrochloride (1:1) |