Pindolol-d7

Modify Date: 2025-08-25 11:55:52

Pindolol-d7 Structure
Pindolol-d7 structure
Common Name Pindolol-d7
CAS Number 1185031-19-9 Molecular Weight 255.36400
Density N/A Boiling Point N/A
Molecular Formula C14H13D7N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pindolol-d7


Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33 nM)[1][2].

 Names

Name 1-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)-3-(1H-indol-4-yloxy)propan-2-ol
Synonym More Synonyms

 Pindolol-d7 Biological Activity

Description Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33 nM)[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Artigas F, et al. Pindolol augmentation of antidepressant response. Curr Drug Targets. 2006;7(2):139-147.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C14H13D7N2O2
Molecular Weight 255.36400
Exact Mass 255.19600
PSA 57.28000
LogP 2.29650

 Synonyms

Apo-pindol
Pindolol-d7
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