DDAO

Modify Date: 2024-01-21 10:45:33

DDAO Structure
DDAO structure
Common Name DDAO
CAS Number 118290-05-4 Molecular Weight 308.159
Density 1.5±0.1 g/cm3 Boiling Point 449.0±45.0 °C at 760 mmHg
Molecular Formula C15H11Cl2NO2 Melting Point N/A
MSDS N/A Flash Point 225.4±28.7 °C

 Use of DDAO


DDAO is a promising near-infrared (NIR) red fluorescent probe with tunable excitation wavelength (600-650 nm) and long emission wavelength (λem = 656 nm). DDAO can de desiged for detection of the activities of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterases[1].

 Names

Name 7-Hydroxy-9H-1,3-dichloro-9,9-dimethylacridin-2-one,DDAO
Synonym More Synonyms

 DDAO Biological Activity

Description DDAO is a promising near-infrared (NIR) red fluorescent probe with tunable excitation wavelength (600-650 nm) and long emission wavelength (λem = 656 nm). DDAO can de desiged for detection of the activities of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterases[1].
Related Catalog
Target

Red fluorescent probe

References

[1]. Hou J1, et al. A near-infrared ratiometric/turn-on fluorescent probe for in vivo imaging of hydrogen peroxide in a murine model of acute inflammation.Anal Chim Acta. 2018 Sep 18;1024:169-176.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 449.0±45.0 °C at 760 mmHg
Molecular Formula C15H11Cl2NO2
Molecular Weight 308.159
Flash Point 225.4±28.7 °C
Exact Mass 307.016693
PSA 49.66000
LogP 3.31
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.666

 Safety Information

Hazard Codes Xn

 Synthetic Route

~79%

DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Corey, Paul F.; Trimmer, Robert W.; Biddlecom, William G. Angewandte Chemie, 1991 , vol. 103, # 12 p. 1694 - 1696

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DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Angewandte Chemie, , vol. 103, # 12 p. 1694 - 1696

~%

DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Angewandte Chemie, , vol. 103, # 12 p. 1694 - 1696

~%

DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Angewandte Chemie, , vol. 103, # 12 p. 1694 - 1696

~%

DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Angewandte Chemie, , vol. 103, # 12 p. 1694 - 1696

~%

DDAO Structure

DDAO

CAS#:118290-05-4

Literature: Angewandte Chemie - International Edition, , vol. 51, # 37 p. 9344 - 9347 Angew. Chem., , vol. 124, # 37 p. 9478 - 9481,5

 Synonyms

2(9H)-Acridinone, 1,3-dichloro-7-hydroxy-9,9-dimethyl-
DDAO
1,3-Dichloro-7-hydroxy-9,9-dimethyl-2(9H)-acridinone
7-Hydroxy-1,3-dichloro-9,9-dimethyl-9 H-acridin-2-one
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