DDAO-C6
Modify Date: 2024-09-25 01:03:47
DDAO-C6 structure
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Common Name | DDAO-C6 | ||
|---|---|---|---|---|
| CAS Number | 2102418-90-4 | Molecular Weight | 420.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23Cl2NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DDAO-C6DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm)[1][2]. |
| Name | DDAO-C6 |
|---|
| Description | DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm)[1][2]. |
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| Related Catalog | |
| In Vitro | DDAO-C6 (100 μM; 2 h; 32 ℃) has been used to visually identify intestinal fungi, Trichosporon asahii Y2, that exhibits high lipase expression from human feces. T. asahii Y2 promotes nutritional obesity in mice[1]. DDAO-C6 (10 μM; 30 min; 37 ℃) exerts enzymatic hydrolysis mediated by lipase with different concentrations (0, 2, 4, 6, 8, 12, 20, 25, 30, 40, and 50 μg/mL), results a linear relationship between the fluorescence intensities and lipase concentrations[1]. DDAO-C6 (50 μM; 6 h; 32 ℃) can be used to sense lipase activity, while is applied in colonies incubation, DDAO-C6 products a red fluorescence signal, suggesting the existence of active lipase[1]. DDAO-C6 hydrolysates have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 550-600 nm, fluorescence emission spectrum detection 630-700 nm[2]. |
| In Vivo | DDAO-C6 can be used to guide the rapid identification and cultivation of lipase active fungal strains from intestinal microbes in human feces, which is a potential technique for the biological investigation of intestinal microbes[2]. |
| References |
| Molecular Formula | C22H23Cl2NO3 |
|---|---|
| Molecular Weight | 420.33 |