DDAO

Names

[ Name ]:
DDAO

[Synonym ]:
2(9H)-Acridinone, 1,3-dichloro-7-hydroxy-9,9-dimethyl-
DDAO
1,3-Dichloro-7-hydroxy-9,9-dimethyl-2(9H)-acridinone
7-Hydroxy-1,3-dichloro-9,9-dimethyl-9 H-acridin-2-one

Biological Activity

[Description]:

DDAO is a promising near-infrared (NIR) red fluorescent probe with tunable excitation wavelength (600-650 nm) and long emission wavelength (λem = 656 nm). DDAO can de desiged for detection of the activities of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterases[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

Red fluorescent probe

[References]

[1]. Hou J1, et al. A near-infrared ratiometric/turn-on fluorescent probe for in vivo imaging of hydrogen peroxide in a murine model of acute inflammation.Anal Chim Acta. 2018 Sep 18;1024:169-176.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
449.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₁Cl₂NO₂

[ Molecular Weight ]:
308.159

[ Flash Point ]:
225.4±28.7 °C

[ Exact Mass ]:
307.016693

[ PSA ]:
49.66000

[ LogP ]:
3.31

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.666

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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