Nebracetam hydrochloride

Modify Date: 2025-08-30 19:07:33

Nebracetam hydrochloride Structure
Nebracetam hydrochloride structure
Common Name Nebracetam hydrochloride
CAS Number 1177279-49-0 Molecular Weight 240.73
Density N/A Boiling Point N/A
Molecular Formula C12H17ClN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nebracetam hydrochloride


Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].

 Names

Name Nebracetam hydrochloride

 Nebracetam hydrochloride Biological Activity

Description Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i[1].
Related Catalog
In Vivo Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms[2]. Animal Model: Male Wistar rats weighing 200-250 g[2]. Dosage: 10, 20 mg/kg. Administration: P.O. (single dose). Result: Able to correct this scopolamine-induced disruption of spatial cognition.
References

[1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80.

[2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26.

 Chemical & Physical Properties

Molecular Formula C12H17ClN2O
Molecular Weight 240.73
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