Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt structure
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Common Name | Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt | ||
|---|---|---|---|---|
| CAS Number | 117399-94-7 | Molecular Weight | 2491.902 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 2467.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C109H159N25O32S5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 1446.0±34.3 °C | |
Use of Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate saltEndothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB. |
| Name | Endothelin 1 |
|---|---|
| Synonym | More Synonyms |
| Description | Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB. |
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| Related Catalog | |
| Target |
ETA and ETB[1] |
| In Vitro | Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a vasoconstrictive action, ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species. It is claimed that ET-1 induces proinflammatory mechanisms, increasing superoxide anion production and cytokine secretion[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 2467.3±65.0 °C at 760 mmHg |
| Molecular Formula | C109H159N25O32S5 |
| Molecular Weight | 2491.902 |
| Flash Point | 1446.0±34.3 °C |
| Exact Mass | 2490.018555 |
| PSA | 1035.13000 |
| LogP | -0.36 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.556 |
| Storage condition | −20°C |
| Water Solubility | 1% acetic acid: >1 mg/mL | Soluble in water. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | T+ |
| RIDADR | 2811.0 |
| WGK Germany | 3 |
| RTECS | KE9446500 |
| Hazard Class | 6.1 |
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ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes.
Biochem. Pharmacol. 90(4) , 406-13, (2014) Endothelin-1 (ET-1) induces lipolysis in adipocytes, where ET-1 chronic exposure results in insulin resistance (IR) through suppression of glucose transporter (GLUT)4 translocation to the plasma membr... |
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HJP272, a novel endothelin receptor antagonist, attenuates lipopolysaccharide-induced acute lung injury in hamsters.
Lung 192(5) , 803-10, (2014) Previous studies from this laboratory indicate that endothelin-1 (ET-1), a potent vasoconstrictor, may play an important role in lipopolysaccharide (LPS)-induced release of neutrophils from the pulmon... |
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Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.
Biochem. Pharmacol. 94(2) , 91-100, (2015) Important structural differences imply that human and mouse mast cell chymases may differ with respect to their enzymatic properties. We compared in this study the catalytic efficiencies of recombinan... |
| MFCD00133305 |
| CSCSSLMDKECVYFCHLDIIW |
| Endothelin 1 (swine, human) |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
- Price: Check
- Purity: 97.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: CSCSSLMDKECVYFCHLDIIW
- Price: $Inquiry/1g
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Jackie Yang
- Email: ymbetter@glbiochem.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
- Price: ￥2828.0/1mg ￥10758.0/5mg
- Purity: 97.0%
- Delivery: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
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