Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
Names
[ CAS No. ]:
117399-94-7
[ Name ]:
Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt
[Synonym ]:
MFCD00133305
CSCSSLMDKECVYFCHLDIIW
Endothelin 1 (swine, human)
Biological Activity
[Description]:
[Related Catalog]:
[Target]
ETA and ETB[1]
[In Vitro]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
2467.3±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C109H159N25O32S5
[ Molecular Weight ]:
2491.902
[ Flash Point ]:
1446.0±34.3 °C
[ Exact Mass ]:
2490.018555
[ PSA ]:
1035.13000
[ LogP ]:
-0.36
[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.556
[ Storage condition ]:
−20°C
[ Water Solubility ]:
1% acetic acid: >1 mg/mL | Soluble in water.
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T+
[ RIDADR ]:
2811.0
[ WGK Germany ]:
3
[ RTECS ]:
KE9446500
[ Hazard Class ]:
6.1
Articles
Biochem. Pharmacol. 90(4) , 406-13, (2014)
Endothelin-1 (ET-1) induces lipolysis in adipocytes, where ET-1 chronic exposure results in insulin resistance (IR) through suppression of glucose transporter (GLUT)4 translocation to the plasma membr...
HJP272, a novel endothelin receptor antagonist, attenuates lipopolysaccharide-induced acute lung injury in hamsters.Lung 192(5) , 803-10, (2014)
Previous studies from this laboratory indicate that endothelin-1 (ET-1), a potent vasoconstrictor, may play an important role in lipopolysaccharide (LPS)-induced release of neutrophils from the pulmon...
Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.Biochem. Pharmacol. 94(2) , 91-100, (2015)
Important structural differences imply that human and mouse mast cell chymases may differ with respect to their enzymatic properties. We compared in this study the catalytic efficiencies of recombinan...