D-Luciferin potassium salt
Modify Date: 2024-01-02 23:22:09
D-Luciferin potassium salt structure
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Common Name | D-Luciferin potassium salt | ||
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| CAS Number | 115144-35-9 | Molecular Weight | 318.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H7KN2O3S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of D-Luciferin potassium saltD-Luciferin potassium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects. |
| Name | D-Luciferin potassium salt |
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| Synonym | More Synonyms |
| Description | D-Luciferin potassium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects. |
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| Related Catalog | |
| In Vitro | D-luciferin is the natural substrate of the enzyme luciferase (Luc), that catalyzes the production of the typical yellowgreen light of fireflies.The present review covers the synthesis of D-luciferin and derivatives or analogues that are substrates or inhibitors of the luciferase from the American firefly Photinus pyralis, the enzyme more frequently used in techniques of in vitro and optical imaging[1]. |
| In Vivo | Bioluminescence imaging (BLI) using the firefly luciferase (Fluc) as a reporter gene and D-luciferin as a substrate is currently the most widely employed technique. The total signal intensity is plotted against the time after D-luciferin injection to generate a time-intensity curve. In addition to the peak signal, the signals at fixed time points (5, 10, 15, and 20 min) after D-luciferin injection are determined as alternatives to the peak signal. The signal in a given time-intensity curve is normalized for the peak signal in the curve to represent the pattern of temporal changes after D-luciferin injection[2]. |
| Animal Admin | Mice[2] In vivo BLI is performed using a cooled charge-coupled device camera system (IVIS Imaging System 100) 3, 5, 7, 10, 12, 14, 19, 21, 24, and 28 days after the inoculation of HCT116-Luc cells. Mice are injected with 75 mg/kg D-luciferin in 100 L of phosphate-buffered saline subcutaneously near the scapula and were placed in the light-tight chamber of the imaging system under isoflurane anesthesia. Beginning 5 min after injection, dorsal luminescent images with an exposure time of 1 s are acquired sequentially at a rate of one image per min until 20 min after D-luciferin injection. Data acquisition is continued until 40 min postinjection on days 3 or 5 and until 25 min on day 7, because of the prolonged time course of light emission. Binning is 4 and the field of view is 15 cm. |
| References |
| Molecular Formula | C11H7KN2O3S2 |
|---|---|
| Molecular Weight | 318.41 |
| PSA | 136.32000 |
| LogP | 1.38410 |
| Storage condition | ?20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Brazilin Isolated from Caesalpinia sappan suppresses nuclear envelope reassembly by inhibiting barrier-to-autointegration factor phosphorylation.
J. Pharmacol. Exp. Ther. 352(1) , 175-84, (2014) To date, many anticancer drugs have been developed by directly or indirectly targeting microtubules, which are involved in cell division. Although this approach has yielded many anticancer drugs, thes... |
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Comparative study of the photoprotolytic reactions of D-luciferin and oxyluciferin.
J. Phys. Chem. A 116 , 7452-7461, (2012) Optical steady-state and time-resolved spectroscopic methods were used to study the photoprotolytic reaction of oxyluciferin, the active bioluminescence chromophore of the firefly's luciferase-catalyz... |
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Label-free phenotypic profiling identified D-luciferin as a GPR35 agonist.
PLoS ONE 7 , e34934, (2012) Fluorescent and luminescent probes are essential to both in vitro molecular assays and in vivo imaging techniques, and have been extensively used to measure biological function. However, little is kno... |
| 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, potassium salt, (4S)- (1:1) |
| MFCD00044928 |
| D-Luciferin potassium salt |
| (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid potassium salt |
| Firefly Luciferin Potassium |
| Potassium (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate |
| Potassium (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: D-Luciferin potassium salt
- Price: ￥10048.0/1g ￥998.0/25mg ￥1838.0/100mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: D-Luciferin (potassium salt)
- Price: $550.0/1g $1600.0/5g $2800.0/10g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: D-luciferin potassium salt
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: D-Luciferin potassium salt
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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