N-Hydroxysuccinimidyl Pyrenebutanoate

Modify Date: 2024-01-03 07:01:33

N-Hydroxysuccinimidyl Pyrenebutanoate Structure
N-Hydroxysuccinimidyl Pyrenebutanoate structure
Common Name N-Hydroxysuccinimidyl Pyrenebutanoate
CAS Number 114932-60-4 Molecular Weight 385.412
Density 1.4±0.1 g/cm3 Boiling Point 590.9±43.0 °C at 760 mmHg
Molecular Formula C24H19NO4 Melting Point 132-136ºC(lit.)
MSDS Chinese USA Flash Point 311.2±28.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of N-Hydroxysuccinimidyl Pyrenebutanoate


1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker which can be used to fabricate some electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is commonly found in organic chemistry or biochemistry where it is used as an activating reagent for carboxylic acids[1][2].

 Names

Name N-Hydroxysuccinimidyl Pyrenebutanoate
Synonym More Synonyms

 N-Hydroxysuccinimidyl Pyrenebutanoate Biological Activity

Description 1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker which can be used to fabricate some electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is commonly found in organic chemistry or biochemistry where it is used as an activating reagent for carboxylic acids[1][2].
Related Catalog
References

[1]. Benvidi A, et al. Comparison of impedimetric detection of DNA hybridization on the various biosensors based on modified glassy carbon electrodes with PANHS and nanomaterials of RGO and MWCNTs. Talanta. 2016 Jan 15;147:621-7.

[2]. Tian J, et al. Biosensing platform based on graphene oxide via self-assembly induced by synergic interactions. Anal Biochem. 2014 Sep 1;460:16-21.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 590.9±43.0 °C at 760 mmHg
Melting Point 132-136ºC(lit.)
Molecular Formula C24H19NO4
Molecular Weight 385.412
Flash Point 311.2±28.2 °C
Exact Mass 385.131409
PSA 63.68000
LogP 3.77
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.739

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Synthetic Route

~79%

N-Hydroxysuccinimidyl Pyrenebutanoate Structure

N-Hydroxysuccin...

CAS#:114932-60-4

Literature: Li, Dong; Song, Jie; Yin, Panchao; Simotwo, Silas; Bassler, Andrew J.; Aung, Yuyu; Roberts, James E.; Hardcastle, Kenneth I.; Hill, Craig L.; Liu, Tianbo Journal of the American Chemical Society, 2011 , vol. 133, # 35 p. 14010 - 14016

~%

N-Hydroxysuccinimidyl Pyrenebutanoate Structure

N-Hydroxysuccin...

CAS#:114932-60-4

Literature: Restituyo, Jose A.; Comstock, Lindsay R.; Petersen, Scott G.; Stringfellow, Thomas; Rajski, Scott R. Organic Letters, 2003 , vol. 5, # 23 p. 4357 - 4360

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 Synonyms

1-{[4-(1-Pyrenyl)butanoyl]oxy}-2,5-pyrrolidinedione
MFCD00077403
2,5-Pyrrolidinedione, 1-[1-oxo-4-(1-pyrenyl)butoxy]-
1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&
1-Pyrenebutyric acid N-hydroxysuccinimide ester
2,5-Pyrrolidinedione, 1-(1-oxo-4-(1-pyrenyl)butoxy)-