N-Hydroxysuccinimidyl Pyrenebutanoate

Names

[ Name ]:
N-Hydroxysuccinimidyl Pyrenebutanoate

[Synonym ]:
1-{[4-(1-Pyrenyl)butanoyl]oxy}-2,5-pyrrolidinedione
MFCD00077403
2,5-Pyrrolidinedione, 1-[1-oxo-4-(1-pyrenyl)butoxy]-
1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&
1-Pyrenebutyric acid N-hydroxysuccinimide ester
2,5-Pyrrolidinedione, 1-(1-oxo-4-(1-pyrenyl)butoxy)-

Biological Activity

[Description]:

1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker which can be used to fabricate some electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is commonly found in organic chemistry or biochemistry where it is used as an activating reagent for carboxylic acids[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Benvidi A, et al. Comparison of impedimetric detection of DNA hybridization on the various biosensors based on modified glassy carbon electrodes with PANHS and nanomaterials of RGO and MWCNTs. Talanta. 2016 Jan 15;147:621-7.

[2]. Tian J, et al. Biosensing platform based on graphene oxide via self-assembly induced by synergic interactions. Anal Biochem. 2014 Sep 1;460:16-21.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
590.9±43.0 °C at 760 mmHg

[ Melting Point ]:
132-136ºC(lit.)

[ Molecular Formula ]:
C₂₄H₁₉NO₄

[ Molecular Weight ]:
385.412

[ Flash Point ]:
311.2±28.2 °C

[ Exact Mass ]:
385.131409

[ PSA ]:
63.68000

[ LogP ]:
3.77

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.739

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Real-time label-free quantitative fluorescence microscopy-based detection of ATP using a tunable fluorescent nano-aptasensor platform.

Nanoscale 7 , 19663-72, (2015)

Although real-time label-free fluorescent aptasensors based on nanomaterials are increasingly recognized as a useful strategy for the detection of target biomolecules with high fidelity, the lack of a...

Facile hydrothermal growth graphene/ZnO nanocomposite for development of enhanced biosensor.

Anal. Chim. Acta 903 , 131-41, (2015)

Graphene/zinc oxide nanocomposite was synthesised via a facile, green and efficient approach consisted of novel liquid phase exfoliation and solvothermal growth for sensing application. Highly pristin...