Camptothecin-20(S)-O-propionate hydrate

Modify Date: 2024-03-20 07:39:07

Camptothecin-20(S)-O-propionate hydrate structure	Common Name	Camptothecin-20(S)-O-propionate hydrate
	CAS Number	1147090-70-7	Molecular Weight	458.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₆N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Camptothecin-20(S)-O-propionate hydrate

Camptothecin-20(S)-O-propionate (Camptothecin-20-O-propionate) hydrate, the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate hydrate is a topoisomerase-Ι inhibitor[1][2].

Name	Camptothecin-20(S)-O-propionate hydrate

Description	Camptothecin-20(S)-O-propionate (Camptothecin-20-O-propionate) hydrate, the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate hydrate is a topoisomerase-Ι inhibitor[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Xing Liu, et al. Correlation between the sensitivity of tumors to treatment with CZ48 and local concentrations of the active metabolite CPT within the tumors. Biomed Rep. 2013 Mar;1(2):202-206. [2]. Zhisong Cao, et al. Crystalline camptothecin-20(S)-O-propionate hydrate: a novel anticancer agent with strong activity against 19 human tumor xenografts. Cancer Res. 2009 Jun 1;69(11):4742-9.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

References

[1]. Xing Liu, et al. Correlation between the sensitivity of tumors to treatment with CZ48 and local concentrations of the active metabolite CPT within the tumors. Biomed Rep. 2013 Mar;1(2):202-206.

[2]. Zhisong Cao, et al. Crystalline camptothecin-20(S)-O-propionate hydrate: a novel anticancer agent with strong activity against 19 human tumor xenografts. Cancer Res. 2009 Jun 1;69(11):4742-9.

Molecular Formula	C₂₃H₂₆N₂O₈
Molecular Weight	458.46

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Camptothecin-20(S)-O-propionate hydrate

Use of Camptothecin-20(S)-O-propionate hydrate

Names

Camptothecin-20(S)-O-propionate hydrate Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.