1147090-70-7

1147090-70-7 structure

Name: Camptothecin-20(S)-O-propionate hydrate
Chemical Name: Camptothecin-20(S)-O-propionate hydrate
CAS Number: 1147090-70-7
Molecular Formula: C₂₃H₂₆N₂O₈
Molecular Weight: 458.46
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2024-03-20 07:39:07
Modify Date: 2024-03-20 07:39:07
Camptothecin-20(S)-O-propionate (Camptothecin-20-O-propionate) hydrate, the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate hydrate is a topoisomerase-Ι inhibitor[1][2].

Name	Camptothecin-20(S)-O-propionate hydrate

Description	Camptothecin-20(S)-O-propionate (Camptothecin-20-O-propionate) hydrate, the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate hydrate is a topoisomerase-Ι inhibitor[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Xing Liu, et al. Correlation between the sensitivity of tumors to treatment with CZ48 and local concentrations of the active metabolite CPT within the tumors. Biomed Rep. 2013 Mar;1(2):202-206. [2]. Zhisong Cao, et al. Crystalline camptothecin-20(S)-O-propionate hydrate: a novel anticancer agent with strong activity against 19 human tumor xenografts. Cancer Res. 2009 Jun 1;69(11):4742-9.

Molecular Formula	C₂₃H₂₆N₂O₈
Molecular Weight	458.46