Caryophyllene oxide

Modify Date: 2024-01-01 20:07:51

Caryophyllene oxide structure	Common Name	Caryophyllene oxide
	CAS Number	1139-30-6	Molecular Weight	220.350
	Density	1.0±0.1 g/cm3	Boiling Point	279.7±19.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄O	Melting Point	62-63ºC(lit.)
	MSDS	Chinese USA	Flash Point	119.7±19.5 °C
	Symbol	GHS07	Signal Word	Warning

Use of Caryophyllene oxide

Caryophyllene oxide, isolated from from Annona squamosa L. bark., possesses analgesic and anti-inflammatory activity[1].

Name	(-)-Caryophyllene oxide
Synonym	More Synonyms

Description	Caryophyllene oxide, isolated from from Annona squamosa L. bark., possesses analgesic and anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Chavan MJ, et al. Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark. Phytomedicine. 2010 Feb;17(2):149-51.

Density	1.0±0.1 g/cm3
Boiling Point	279.7±19.0 °C at 760 mmHg
Melting Point	62-63ºC(lit.)
Molecular Formula	C₁₅H₂₄O
Molecular Weight	220.350
Flash Point	119.7±19.5 °C
Exact Mass	220.182709
PSA	12.53000
LogP	4.57
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.507

Caryophyllene oxide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RP5530000

CHEMICAL NAME :: 5-Oxatricyclo(8.2.0.0(sup 4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-

CAS REGISTRY NUMBER :: 1139-30-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H24-O

MOLECULAR WEIGHT :: 220.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/38
Safety Phrases	26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	RP5530000
HS Code	29109000

trans-Caryophyllene

CAS#:87-44-5

Caryophyllene oxide

CAS#:1139-30-6

N/A

CAS#:103475-43-0

Literature: Helvetica Chimica Acta, , vol. 77, # 1 p. 36 - 40

trans-Caryophyllene

CAS#:87-44-5

Caryophyllene oxide

CAS#:1139-30-6

Literature: Helvetica Chimica Acta, , vol. 66, # 7 p. 2223 - 2235

Perbenzoic acid

CAS#:93-59-4

trans-Caryophyllene

CAS#:87-44-5

Caryophyllene oxide

CAS#:1139-30-6

Literature: Chemische Berichte, , vol. 80, p. 56,62 Journal of the Chemical Society, , p. 537,539

perphthalic acid

CAS#:2311-91-3

trans-Caryophyllene

CAS#:87-44-5

Caryophyllene oxide

CAS#:1139-30-6

Literature: Journal of the Chemical Society, , p. 4336,4339

trans-Caryophyllene

CAS#:87-44-5

~53%

Caryophyllene oxide

CAS#:1139-30-6

(2R,5R,6R)-2,12...

CAS#:60444-80-6

(1R,4R,6R,9S,10...

CAS#:60479-10-9

Literature: Bulletin de la Societe Chimique de France, , vol. 132, # 8 p. 836 - 842

trans-Caryophyllene

CAS#:87-44-5

(1R,4R,5R,9S,11...

CAS#:118122-82-0

(1R,4R,5R,9S,11...

CAS#:108525-13-9

14-hydroxycaryo...

CAS#:73510-14-2

Detail

Literature: Phytochemistry (Elsevier), , vol. 29, # 1 p. 115 - 120

Precursor 3
CAS#:87-44-5 trans-Caryophyllene CAS#:93-59-4 Perbenzoic acid CAS#:2311-91-3 perphthalic acid
DownStream 1
CAS#:32214-91-8 caryophyllene a...

Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense.

J. Nat. Prod. 74 , 559-66, (2011)

In a survey of plants from Ecuador with antiprotozoal activity, Cupania cinerea was found to show significant in vitro activity against the Plasmodium falciparum K1 strain and Trypanosoma brucei rhode...

Microbial transformation and butyrylcholinesterase inhibitory activity of (-)-caryophyllene oxide and its derivatives.

J. Nat. Prod. 69 , 1429-34, (2006)

Microbial transformation of the sesquiterpene (-)-caryophyllene oxide (1) [(1R,4R,5R,9S)-4,5-epoxycaryophyllan-8(13)-ene] by a number of fungi, using a standard two-stage fermentation technique, has a...

H.M.R. Hoffmann, U. Vogt

Synlett , 581, (1990)

(1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane

(-)-b-Caryophyllene oxide

6,7-Epoxy-3(15)-caryophyllene

(−)-Caryophyllene oxide

4b,5a-Epoxycaryophyllene

(-)-b-Caryophyllene epoxide

(1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]dodecane

(-)-Epoxydihydrocaryophyllene

(-)-caryophyllene oxide

5-Oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-

b-Caryophyllene oxide

Caryophyllene 4b,5a-oxide

β-Caryophyllene oxide

EINECS 214-519-7

MFCD00134216

b-Caryophyllene epoxide

trans-caryophyllene oxide

5-Oxatricyclo[8.2.0.0]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-

caryophyllene oxide

(−)-Epoxycaryophyllene

BioBioPha
China
Product Name: Caryophyllene oxide
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Caryophyllene oxide
Price: ￥888.0/100mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: b-Caryophyllene oxide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Caryophyllene oxide suppliers

Caryophyllene oxide price

Caryophyllene oxide

Use of Caryophyllene oxide

Names