H2N-PEG2-CH2COOtBu

Modify Date: 2024-01-09 17:45:17

H2N-PEG2-CH2COOtBu Structure
H2N-PEG2-CH2COOtBu structure
Common Name H2N-PEG2-CH2COOtBu
CAS Number 1122484-77-8 Molecular Weight 219.28
Density N/A Boiling Point N/A
Molecular Formula C10H21NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H2N-PEG2-CH2COOtBu


H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name H2N-PEG2-CH2COOtBu
Synonym More Synonyms

 H2N-PEG2-CH2COOtBu Biological Activity

Description H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H21NO4
Molecular Weight 219.28

 Safety Information

Hazard Codes C

 Synonyms

MFCD24395885