DC Chemicals Limited
China
Product Name: H2N-PEG2-CH2COOtBu
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1122484-77-8

1122484-77-8 structure

1122484-77-8 structure

Name: H2N-PEG2-CH2COOtBu
Chemical Name: H2N-PEG2-CH2COOtBu
CAS Number: 1122484-77-8
Molecular Formula: C₁₀H₂₁NO₄
Molecular Weight: 219.28
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-09-11 22:43:01
Modify Date: 2024-01-09 17:45:17
H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	H2N-PEG2-CH2COOtBu
Synonyms	MFCD24395885

Description	H2N-PEG2-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₀H₂₁NO₄
Molecular Weight	219.28

Hazard Codes	C