hCAIX/XII-IN-4

Modify Date: 2025-09-07 17:40:18

hCAIX/XII-IN-4 Structure
hCAIX/XII-IN-4 structure
Common Name hCAIX/XII-IN-4
CAS Number 1119200-33-7 Molecular Weight 364.35
Density N/A Boiling Point N/A
Molecular Formula C20H16N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hCAIX/XII-IN-4


hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

 Names

Name hCAIX/XII-IN-4

 hCAIX/XII-IN-4 Biological Activity

Description hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
Related Catalog
Target

Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)[1]

References

[1]. Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

 Chemical & Physical Properties

Molecular Formula C20H16N2O5
Molecular Weight 364.35
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