2451479-57-3

2451479-57-3 structure

2451479-57-3 structure

Name: hCAIX-IN-5
Chemical Name: hCAIX-IN-5
CAS Number: 2451479-57-3
Molecular Formula: C₁₈H₁₂FNO₃
Molecular Weight: 309.29
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-07-31 15:38:59
Modify Date: 2024-04-08 11:13:50
hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].

Name	hCAIX-IN-5

Description	hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	KI: >10000 nM (hCAI); >10000 nM (hCAII); 130.7 nM (hCAIV); 829.1 nM (hCAIX)[1]
References	[1]. Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586.

Molecular Formula	C₁₈H₁₂FNO₃
Molecular Weight	309.29