1119200-33-7

1119200-33-7 structure
1119200-33-7 structure
  • Name: hCAIX/XII-IN-4
  • Chemical Name: hCAIX/XII-IN-4
  • CAS Number: 1119200-33-7
  • Molecular Formula: C20H16N2O5
  • Molecular Weight: 364.35
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
  • Create Date: 2022-10-01 17:50:20
  • Modify Date: 2025-09-07 17:40:18
  • hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

Name hCAIX/XII-IN-4
Description hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
Related Catalog
Target

Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)[1]

References

[1]. Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula C20H16N2O5
Molecular Weight 364.35
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