1119200-33-7

1119200-33-7 structure

1119200-33-7 structure

Name: hCAIX/XII-IN-4
Chemical Name: hCAIX/XII-IN-4
CAS Number: 1119200-33-7
Molecular Formula: C₂₀H₁₆N₂O₅
Molecular Weight: 364.35
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-10-01 17:50:20
Modify Date: 2024-04-09 12:02:13
hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

Name	hCAIX/XII-IN-4

Description	hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)[1]
References	[1]. Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula	C₂₀H₁₆N₂O₅
Molecular Weight	364.35