NALTRIBEN MESYLATE

Modify Date: 2025-08-25 14:34:45

NALTRIBEN MESYLATE structure	Common Name	NALTRIBEN MESYLATE
	CAS Number	111555-58-9	Molecular Weight	415.48
	Density	1.5 g/cm3	Boiling Point	605.3ºC at 760 mmHg
	Molecular Formula	C₂₆H₂₅NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	319.9ºC

Use of NALTRIBEN MESYLATE

Naltriben is a selective δ2-opioid receptor antagonist and TRPM7 activator. Naltriben enhances glioblastoma cell migration and invasion. Naltriben can be used in research into neurological diseases and cancer[1][2].

Name	Naltriben
Synonym	More Synonyms

Description	Naltriben is a selective δ2-opioid receptor antagonist and TRPM7 activator. Naltriben enhances glioblastoma cell migration and invasion. Naltriben can be used in research into neurological diseases and cancer[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
References	[1]. Lever JR, et al. Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain. Eur J Pharmacol. 1998 Jun 5;350(2-3):335-44. [2]. Wong R, et al. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells. Oncotarget. 2017 Feb 14;8(7):11239-11248.

Description

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

References

[1]. Lever JR, et al. Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain. Eur J Pharmacol. 1998 Jun 5;350(2-3):335-44.

[2]. Wong R, et al. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells. Oncotarget. 2017 Feb 14;8(7):11239-11248.

Density	1.5 g/cm3
Boiling Point	605.3ºC at 760 mmHg
Molecular Formula	C₂₆H₂₅NO₄
Molecular Weight	415.48
Flash Point	319.9ºC
Exact Mass	511.16600
PSA	128.82000
LogP	4.36020
Vapour Pressure	1.67E-15mmHg at 25°C
Index of Refraction	1.779

Naltrexone Hydr...

CAS#:16676-29-2

(Aminooxy)benze...

CAS#:6092-80-4

~81%

NALTRIBEN MESYLATE

CAS#:111555-58-9

Literature: Portoghese; Sultana; Nagase; Takemori Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 281 - 282

Naltriben mesylate

CAS#:122517-78-6

NALTRIBEN MESYLATE

CAS#:111555-58-9

Literature: PROGENICS PHARMACEUTICALS, INC Patent: WO2009/67275 A1, 2009 ; Location in patent: Page/Page column 140-141 ; WO 2009/067275 A2

Precursor 3
CAS#:16676-29-2 Naltrexone Hydr... CAS#:6092-80-4 (Aminooxy)benze... CAS#:122517-78-6 Naltriben mesylate
DownStream 0

naltrindole benzofuran

C26H25NO4

NTB

HMS2089G18

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.