Pimelic acid

Modify Date: 2024-01-02 08:24:44

Pimelic acid Structure
Pimelic acid structure
Common Name Pimelic acid
CAS Number 111-16-0 Molecular Weight 160.168
Density 1.2±0.1 g/cm3 Boiling Point 353.7±25.0 °C at 760 mmHg
Molecular Formula C7H12O4 Melting Point 103-105 °C(lit.)
MSDS Chinese USA Flash Point 181.9±19.7 °C

 Use of Pimelic acid


Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.

 Names

Name pimelic acid
Synonym More Synonyms

 Pimelic acid Biological Activity

Description Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 353.7±25.0 °C at 760 mmHg
Melting Point 103-105 °C(lit.)
Molecular Formula C7H12O4
Molecular Weight 160.168
Flash Point 181.9±19.7 °C
Exact Mass 160.073563
PSA 74.60000
LogP 0.27
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.476
Stability Stable. Incompatible with oxidizing agents, bases. Combustible.
Water Solubility 25 g/L (13 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK3677000
CHEMICAL NAME :
Pimelic acid
CAS REGISTRY NUMBER :
111-16-0
BEILSTEIN REFERENCE NO. :
1210024
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H12-O4
MOLECULAR WEIGHT :
160.19
WISWESSER LINE NOTATION :
QV5VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,477,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4800 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS TK3677000
HS Code 2917190090

 Synthetic Route

 Customs

HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles6

More Articles
Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Concentrations of riboflavin and related organic acids in children with protein-energy malnutrition.

Am. J. Clin. Nutr. 71(4) , 978-86, (2000)

Riboflavin, flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD) concentrations have been little studied in cases of malnutrition.Our objective was to investigate the effects of malnutri...

Azelaic acid--biochemistry and metabolism.

Acta Derm. Venereol. Suppl. (Stockh.) 143 , 8-13, (1989)

Medium chain length dicarboxylic acids (DA) from C8 to C13 are competitive inhibitors of tyrosinase in vitro. The introduction of electron acceptor groups or electron donor groups into the 2 and/or th...

 Synonyms

Pimefilina [INN-Spanish]
Heptanedioic acid
1,3-dimethyl-7-[2-(pyridin-3-ylmethyl-amino)-ethyl]-3,7-dihydro-purine-2,6-dione
Pimefylline [INN]
Pimelic acid
Pimefyllinum [INN-Latin]
Pimefyllin
7-(ss-3'-Picolylaminoaethyl)-theophyllin
Pimephylline
7-(2-((3-Pyridylmethyl)amino)ethyl)theophylline
heptanedioate
1,7-heptanedioic acid
EINECS 203-840-8
Pimefylline
heptane-1,7-dioic acid
MFCD00004425
UNII-BZQ96WX25F
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