28-Oxooligomycin A

Modify Date: 2024-01-09 02:25:40

28-Oxooligomycin A Structure
28-Oxooligomycin A structure
Common Name 28-Oxooligomycin A
CAS Number 11050-94-5 Molecular Weight 805.046
Density 1.2±0.1 g/cm3 Boiling Point 911.4±65.0 °C at 760 mmHg
Molecular Formula C45H72O12 Melting Point 160-161℃
MSDS N/A Flash Point 260.3±27.8 °C

 Use of 28-Oxooligomycin A


Oligomycin B is an antibiotic isolated from marine Streptomyces, used as an eukaryotic ATP synthase inhibitor, induces apoptosis[1][2].

 Names

Name oligomycin b
Synonym More Synonyms

 28-Oxooligomycin A Biological Activity

Description Oligomycin B is an antibiotic isolated from marine Streptomyces, used as an eukaryotic ATP synthase inhibitor, induces apoptosis[1][2].
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 911.4±65.0 °C at 760 mmHg
Melting Point 160-161℃
Molecular Formula C45H72O12
Molecular Weight 805.046
Flash Point 260.3±27.8 °C
Exact Mass 804.502380
PSA 197.12000
LogP 5.50
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.547
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RK3330000
CHEMICAL NAME :
Oligomycin B
CAS REGISTRY NUMBER :
11050-94-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C45-H72-O12
MOLECULAR WEIGHT :
805.17
WISWESSER LINE NOTATION :
T6-26- A COX GOV NV RV IU WU B&UTJ A1 E1 K1 L1 M1 O1 PQ Q1 SQ S1 TQ U1 D&2 D-& BT6OXVTJ E1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 80,6092,1958

 Safety Information

Hazard Codes Xn: Harmful;T: Toxic;
Risk Phrases 20/21/22-68/20/21/22-22
Safety Phrases 36/37
RIDADR UN 2811
WGK Germany 3
RTECS RK3330000
Packaging Group III
Hazard Class 6.1(b)

 Synonyms

28-Oxooligomycin A
Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone, 22-ethyl-5',6'-dihydro-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27R,28R,29S)-
Oligomycin B
Oligomycin A,28-oxo
Oligomycin B fromStreptomyces diastatochromogenes
28-oxo-oligomycin A
(1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27R,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-5',6'-dihydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,3',9,13(4'H)-tetrone