BIX 02188

Modify Date: 2024-01-02 18:47:36

BIX 02188 Structure
BIX 02188 structure
Common Name BIX 02188
CAS Number 1094614-84-2 Molecular Weight 412.48
Density 1.3±0.1 g/cm3 Boiling Point 615.8±55.0 °C at 760 mmHg
Molecular Formula C25H24N4O2 Melting Point N/A
MSDS N/A Flash Point 326.2±31.5 °C

 Use of BIX 02188


(E/Z)-BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z)-BIX02188 inhibits the catalytic function of purified MEK5 enzyme.(E/Z)-BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].

 Names

Name bix-02188
Synonym More Synonyms

 BIX 02188 Biological Activity

Description (E/Z)-BIX02188 is a MEK5/ERK5 pathway inhibitor. (E/Z)-BIX02188 inhibits the catalytic function of purified MEK5 enzyme.(E/Z)-BIX02188 can be used for the role of MEK5/ERK5 pathway in various biological systems [1].
Related Catalog
References

[1]. Tatake RJ, et al. Identification of pharmacological inhibitors of the MEK5/ERK5 pathway. Biochem Biophys Res Commun. 2008 Dec 5;377(1):120-5.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 615.8±55.0 °C at 760 mmHg
Molecular Formula C25H24N4O2
Molecular Weight 412.48
Flash Point 326.2±31.5 °C
Exact Mass 412.189911
PSA 87.46000
LogP 2.36
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.688

 Safety Information

Hazard Codes Xi

 Synonyms

(3Z)-3-[({3-[(Dimethylamino)methyl]phenyl}amino)(phenyl)methylene]-2-oxo-6-indolinecarboxamide
1H-Indole-6-carboxamide, 3-[[[3-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-, (3Z)-
3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide
bix02188